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Intrapleural tissue plasminogen activator/deoxyribonuclease (tPA/DNase) therapy is increasingly used in pleural infection. Bleeding risks and costs associated with tPA remain the clinical concerns. Our dose de‐escalation series aims to establish… Click to show full abstract
Intrapleural tissue plasminogen activator/deoxyribonuclease (tPA/DNase) therapy is increasingly used in pleural infection. Bleeding risks and costs associated with tPA remain the clinical concerns. Our dose de‐escalation series aims to establish the lowest effective dosing regimen for tPA/DNase. This study assesses the intrapleural use of 2.5 mg tPA/5 mg DNase for pleural infection.
Keywords:
alteplase;
pleural infection;
therapy;
study;
use
Journal Title: Respirology
Year Published: 2022
Link to full text (if available)
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Journal Title: Respirology
Year Published: 2022
Link to full text (if available)
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recommendations!