Smoking disturbs the bronchial‐mucus‐barrier. This study assesses the cellular composition and gene expression shifts of the bronchial‐mucus‐barrier with smoking to understand the mechanism of mucosal damage by cigarette smoke exposure.… Click to show full abstract
Smoking disturbs the bronchial‐mucus‐barrier. This study assesses the cellular composition and gene expression shifts of the bronchial‐mucus‐barrier with smoking to understand the mechanism of mucosal damage by cigarette smoke exposure. We explore whether single‐cell‐RNA‐sequencing (scRNA‐seq) based cellular deconvolution (CD) can predict cell‐type composition in RNA‐seq data.
Keywords:
cellular composition;
bronchial mucus;
mucus barrier
Journal Title: Respirology
Year Published: 2022
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Journal Title: Respirology
Year Published: 2022
Link to full text (if available)
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recommendations!