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Checkpoint inhibitor pneumonitis (CIP), caused by the anti‐programmed cell death‐1 (PD‐1)/programmed cell death ligand‐1 (PD‐L1) antibody, can be a fatal adverse event in cancer patients. However, no predictive biomarkers for… Click to show full abstract
Checkpoint inhibitor pneumonitis (CIP), caused by the anti‐programmed cell death‐1 (PD‐1)/programmed cell death ligand‐1 (PD‐L1) antibody, can be a fatal adverse event in cancer patients. However, no predictive biomarkers for CIP have been identified. Because high‐mobility group box 1 (HMGB1) can aggravate lung injury and potentially increase the immune response, it was investigated as a predictive blood marker.
Keywords:
checkpoint inhibitor;
mobility group;
group box;
high mobility;
inhibitor pneumonitis
Journal Title: Respirology
Year Published: 2022
Link to full text (if available)
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Journal Title: Respirology
Year Published: 2022
Link to full text (if available)
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recommendations!