Neutrophil elastase (NE), is an important host defence against lung pathogens. Maintaining a homeostatic balance between proteases such as NE and anti‐proteases such as secretory leukocyte protease inhibitor (SLPI), is… Click to show full abstract
Neutrophil elastase (NE), is an important host defence against lung pathogens. Maintaining a homeostatic balance between proteases such as NE and anti‐proteases such as secretory leukocyte protease inhibitor (SLPI), is important to prevent tissue damage. In the cystic fibrosis (CF) lung, elevated protease levels and impaired anti‐protease defences contribute to tissue destruction.
               
Click one of the above tabs to view related content.