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Elevated serum cartilage oligomeric matrix protein and the metalloproteinase‐ADAMTS7 levels are associated with vascular calcification in maintenance hemodialysis patients

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Vascular calcification is common in maintenance hemodialysis (HD) patients. Recent studies showed that cartilage oligomeric matrix protein (COMP) could protect blood vessels from calcification, but the role of ADAMTS7 was… Click to show full abstract

Vascular calcification is common in maintenance hemodialysis (HD) patients. Recent studies showed that cartilage oligomeric matrix protein (COMP) could protect blood vessels from calcification, but the role of ADAMTS7 was opposite. We aimed to investigate the relationship between serum COMP, ADAMTS7 levels and vascular calcification scores in HD patients.

Keywords: vascular calcification; cartilage oligomeric; calcification; oligomeric matrix; hemodialysis patients; maintenance hemodialysis

Journal Title: Seminars in Dialysis
Year Published: 2020

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