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Recurrent respiratory tract infections (rRTI) in children represent a challenge in physician's practice and raise the suspicion of an immunological defect, when allergy and other chronic respiratory diseases are excluded… Click to show full abstract
Recurrent respiratory tract infections (rRTI) in children represent a challenge in physician's practice and raise the suspicion of an immunological defect, when allergy and other chronic respiratory diseases are excluded [1]. When major primary antibody deficiencies are excluded [2-4], the diagnosis of Unclassified Primary Antibody Deficiency (UnPAD) or a Specific Antibody Deficiency (SAD) due to a reduced response to purified or conjugate pneumococcal polysaccharide vaccine (PPV-SAD and PCV-SAD, respectively) should be considered [5].
Journal Title: Scandinavian Journal of Immunology
Year Published: 2020
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