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The rheological properties of dermal drug delivery systems are of importance when designing new formulations. Viscosity not only affects features such as spreadability and skin feel, but may also affect… Click to show full abstract
The rheological properties of dermal drug delivery systems are of importance when designing new formulations. Viscosity not only affects features such as spreadability and skin feel, but may also affect the skin penetration of incorporated actives. Data on the latter aspect are controversial. Our objective was to elucidate the relation between viscosity and drug delivery performance of different model hydrogels assuming that enhanced microviscosity might delay drug release and penetration.
Keywords:
penetration cellulose;
viscosity;
penetration;
role viscosity;
viscosity skin;
skin penetration
Journal Title: Skin Research and Technology
Year Published: 2019
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Journal Title: Skin Research and Technology
Year Published: 2019
Link to full text (if available)
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recommendations!