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Dear Editor, First described in 1996 as “transient reactive papulo-translucent acrokeratoderma,” this rare condition was then variously named according to its peculiar clinical appearance, such as “aquagenic syringeal acrokeratoderma,” “aquagenic… Click to show full abstract
Dear Editor, First described in 1996 as “transient reactive papulo-translucent acrokeratoderma,” this rare condition was then variously named according to its peculiar clinical appearance, such as “aquagenic syringeal acrokeratoderma,” “aquagenic palmoplantar keratoderma,” or “transient aquagenic palmar hyperwrinkling.”1-11 The acquired form of aquagenic keratoderma (AAK) usually affects young women, and its pathogenesis has yet to be elucidated. Some hypothesis have been raised, such as dysregulation of the sweating mechanism with accelerated sweat secretion and/or increased salt concentration; increased water-affinity of the stratum corneum defective stratum corneum barrier function; occlusion of
Journal Title: Skin Research and Technology
Year Published: 2020
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