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Characterization and ex vivo evaluation of excised skin samples as substitutes for human dermal barrier in pharmaceutical and dermatological studies

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Excised animal and human skins are frequently used in permeability testing in pharmaceutical research. Several factors exist that may have influence on the results. In the current study some of… Click to show full abstract

Excised animal and human skins are frequently used in permeability testing in pharmaceutical research. Several factors exist that may have influence on the results. In the current study some of the skin parameters that may affect drug permeability were analysed for human, mouse, rat and pig skin.

Keywords: evaluation excised; excised skin; samples substitutes; skin samples; vivo evaluation; characterization vivo

Journal Title: Skin Research and Technology
Year Published: 2022

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