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The role of topical capsaicin gel in pain management during microfocused ultrasound treatment for neck laxity

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The transient receptor potential vanilloid 1 (TRPV1) provides a heat and pain sensation (nociception). Capsaicin, a TRPV1 agonist, has been shown to induce a refractory period in the nerve terminal… Click to show full abstract

The transient receptor potential vanilloid 1 (TRPV1) provides a heat and pain sensation (nociception). Capsaicin, a TRPV1 agonist, has been shown to induce a refractory period in the nerve terminal expressing TRPV1 and create longā€term nerve terminal defunctionalization.

Keywords: topical capsaicin; gel pain; pain; role topical; capsaicin gel; capsaicin

Journal Title: Skin Research and Technology
Year Published: 2022

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