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The distribution of HLA‐DRB3 alleles among HLA‐DRB1*03:01‐positive haplotypes

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HLA‐DRB3 allelic polymorphism on HLA‐DRB1*03:01‐positive haplotypes was investigated among 104 cadaveric donors typed for HLA‐A, ‐B, ‐DRB1, and ‐DRB3. Only HLA‐DRB3*01:01:02 and ‐DRB3*02:02:01:01 alleles were detected among HLA‐DRB1*03:01‐positive individuals and… Click to show full abstract

HLA‐DRB3 allelic polymorphism on HLA‐DRB1*03:01‐positive haplotypes was investigated among 104 cadaveric donors typed for HLA‐A, ‐B, ‐DRB1, and ‐DRB3. Only HLA‐DRB3*01:01:02 and ‐DRB3*02:02:01:01 alleles were detected among HLA‐DRB1*03:01‐positive individuals and their distribution depended on HLA‐B*08 presence: nearly all HLA‐B*08‐positive samples carried DRB3*01:01:02, while HLA‐DRB3*02:02:01:01 was more frequent among HLA‐B*08‐negative subjects.

Keywords: among hla; hla drb1; hla; drb1 positive; hla drb3

Journal Title: HLA
Year Published: 2018

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