LAUSR

The following sequences have been submitted to the Nomenclature Committee since the July, August and September 2021 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report. Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3. In addition, the sequence for the allele DQB1*02:01:14 has been extended and shown to be a new silent variant of the DQB1*02:02 protein group. The allele name DQB1*02:01:14 has been abandoned and the sequence renamed DQB1*02:02:17. Furthermore, the allele DQB1*03:01:01:21Q has been shown to be not expressed, therefore the allele name has been updated to DQB1*03:01:01:21N. All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IPD-IMGT/HLA Database using the sequence submission tool provided. The IPD-IMGT/HLA Database may be accessed via the World Wide Web at: www.ebi.ac.uk/ipd/imgt/hla