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Diagnostic open brain biopsy following initial negative results of cerebrospinal fluid assessment for Toxoplasma

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Cerebral toxoplasmosis is a rare but fatal complication after allogeneic hematopoietic stem cell transplantation (HSCT), and reaching an accurate antemortem diagnosis with pathological proof is difficult.1,2 We describe herein the… Click to show full abstract

Cerebral toxoplasmosis is a rare but fatal complication after allogeneic hematopoietic stem cell transplantation (HSCT), and reaching an accurate antemortem diagnosis with pathological proof is difficult.1,2 We describe herein the clinical course of a patient with cerebral toxoplasmosis following allogeneic HSCT. The diagnosis was successfully made by aggressive open brain biopsy following initial negative results from cerebrospinal fluid (CSF) assessment for Toxoplasma. This article is protected by copyright. All rights reserved.

Keywords: biopsy following; open brain; brain biopsy; initial negative; negative results; following initial

Journal Title: Transplant Infectious Disease
Year Published: 2017

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