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Voriconazole concentration is inversely correlated with corticosteroid usage in immunocompromised patients

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Voriconazole (VRCZ) is a broad‐spectrum antifungal agent that can be administered both orally and intravenously. A high level of intra‐ and interindividual variability in serum drug therapeutic concentrations has been… Click to show full abstract

Voriconazole (VRCZ) is a broad‐spectrum antifungal agent that can be administered both orally and intravenously. A high level of intra‐ and interindividual variability in serum drug therapeutic concentrations has been reported. We analyzed the influence of corticosteroid use on serum VRCZ concentration by assessing the correlation between corticosteroid dose and VRCZ trough level.

Keywords: corticosteroid usage; voriconazole concentration; inversely correlated; concentration inversely; correlated corticosteroid; concentration

Journal Title: Transplant Infectious Disease
Year Published: 2018

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