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Hepatitis C genotype change after transplantation utilizing hepatitis C positive donor organs

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A shortage in organs for transplantation has led to the increased use of hepatitis C (HCV) infected donor organs for solid organ transplant recipients infected with HCV. However, the donor… Click to show full abstract

A shortage in organs for transplantation has led to the increased use of hepatitis C (HCV) infected donor organs for solid organ transplant recipients infected with HCV. However, the donor HCV genotype is not routinely checked or known prior to transplant. Here, we report 4 cases of genotype conversion after transplantation in patients receiving HCV infected donor organs. This change in genotype may potentially impact HCV progression as well as treatment choice for these patients.

Keywords: genotype change; transplantation; donor organs; hepatitis genotype; change transplantation

Journal Title: Transplant Infectious Disease
Year Published: 2018

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