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A mathematical model to describe survival among liver recipients from deceased donors with risk of transmitting infectious encephalitis pathogens

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Between 2002 and 2013, the organs of 13 deceased donors with infectious encephalitis were transplanted, causing infections in 23 recipients. As a consequence, organs from donors showing symptoms of encephalitis… Click to show full abstract

Between 2002 and 2013, the organs of 13 deceased donors with infectious encephalitis were transplanted, causing infections in 23 recipients. As a consequence, organs from donors showing symptoms of encephalitis (increased probability of infectious encephalitis (IPIE) organs) might be declined. We had previously characterized the risk of IPIE organs using data available to most transplant teams and not requiring special diagnostic tests. If the probability of infection is low, the benefits of a transplant from a donor with suspected infectious encephalitis might outweigh the risk and could be lifesaving for some transplant candidates.

Keywords: deceased donors; model describe; describe survival; infectious encephalitis; encephalitis; mathematical model

Journal Title: Transplant Infectious Disease
Year Published: 2019

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