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Neutropenia and renal dysfunction due to intravesical cidofovir for virus‐associated hemorrhagic cystitis after kidney and allogenic hematopoietic stem cell transplantations

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We present a patient with virus‐associated hemorrhagic cystitis who underwent kidney and allogenic hematopoietic stem cell transplantations (allo‐HSCT). Six months post‐allo‐HSCT, adenovirus hemorrhagic cystitis occurred, which has been in remission… Click to show full abstract

We present a patient with virus‐associated hemorrhagic cystitis who underwent kidney and allogenic hematopoietic stem cell transplantations (allo‐HSCT). Six months post‐allo‐HSCT, adenovirus hemorrhagic cystitis occurred, which has been in remission after a single dose of intravesical cidofovir. This might cause prolonged neutropenia and nephrotoxicity, suggesting cidofovir absorption in the blood.

Keywords: cystitis; kidney allogenic; allogenic hematopoietic; associated hemorrhagic; virus associated; hemorrhagic cystitis

Journal Title: Transplant Infectious Disease
Year Published: 2019

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