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Assessing the composition of immune responses to SARS‐CoV‐2 vaccines is critical for our understanding of protective immunity, especially for immune compromised patients. The Pfizer (BNT162b2) vaccination showed >90% efficacy in… Click to show full abstract
Assessing the composition of immune responses to SARS‐CoV‐2 vaccines is critical for our understanding of protective immunity, especially for immune compromised patients. The Pfizer (BNT162b2) vaccination showed >90% efficacy in protecting individuals from infection. However, these studies did not examine responses in immunocompromised kidney transplant patients (KT). Subsequent reports in KT have shown severe deficiencies in Spike‐specific immunoglobin G (IgG) responses prompting booster vaccinations, but a broader understanding of T‐cell immunity to vaccinating is lacking.
Journal Title: Transplant Infectious Disease
Year Published: 2022
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