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Platelet donor selection for HLA‐immunised patients; the impact of donor‐specific HLA antibody levels

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Approximately 20% of patients with a recurrently poor platelet transfusion increment show human leukocyte antigen (HLA) alloantibodies. The aim of this study was to analyse the impact of mean fluorescence… Click to show full abstract

Approximately 20% of patients with a recurrently poor platelet transfusion increment show human leukocyte antigen (HLA) alloantibodies. The aim of this study was to analyse the impact of mean fluorescence intensity (MFI) levels of donor‐specific HLA antibodies and the feasibility of the HLAMatchmaker algorithm in donor selection.

Keywords: specific hla; hla; platelet donor; donor selection; donor specific

Journal Title: Transfusion Medicine
Year Published: 2017

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