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A novel A allele with c.689G>T mutation identified in a Chinese individual

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A BO is the most important blood group system in both transfusion and transplantation medicine. Subgroups are defined by weakly expressed A or B antigen, respectively, and result in typing… Click to show full abstract

A BO is the most important blood group system in both transfusion and transplantation medicine. Subgroups are defined by weakly expressed A or B antigen, respectively, and result in typing anomalies. Since the discovery of the ABO gene, several hundred variant alleles resulting in various phenotypes have been characterized and reported in the blood group allele tables of the International Society of Blood Transfusion (ISBT). Here we report the finding of a novel variant A allele.

Keywords: identified chinese; 689g mutation; novel allele; allele 689g; chinese individual; mutation identified

Journal Title: Transfusion
Year Published: 2018

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