Ammonia in the plasma usually does not pass through the blood–brain barrier (BBB). However, it can affect the brain as a neurotoxin in neonates with anemia of prematurity. Excess intake… Click to show full abstract
Ammonia in the plasma usually does not pass through the blood–brain barrier (BBB). However, it can affect the brain as a neurotoxin in neonates with anemia of prematurity. Excess intake of ammonia should therefore be restricted in conditions involving BBB breakdown, such as in premature neonates. A potassium adsorption filter (PAF) can remove not only potassium, but also ammonia from red blood cell (RBC) solution. PAF for neonates (PAF‐n) has been recently introduced using small satellite packs. We evaluated the effects of PAF‐n on the removal of ammonia and potassium from RBC solution in small satellite packs.
               
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