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Hemolytic adverse effects of intravenous immunoglobulin: modeling predicts risk reduction with anti‐A/B immunoaffinity chromatography and to a lesser extent with anti‐A donor screening

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The risk of hemolytic events (HEs) with intravenous immunoglobulin (IVIG) therapy appears to be linked to isoagglutinins (anti‐A and anti‐B) in the product. Patient risk factors include high IVIG dose,… Click to show full abstract

The risk of hemolytic events (HEs) with intravenous immunoglobulin (IVIG) therapy appears to be linked to isoagglutinins (anti‐A and anti‐B) in the product. Patient risk factors include high IVIG dose, blood group, and underlying inflammatory state.

Keywords: intravenous immunoglobulin; risk; immunoglobulin modeling; hemolytic adverse; effects intravenous; adverse effects

Journal Title: Transfusion
Year Published: 2018

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