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Activity Disclosures No commercial support has been accepted related to the development or publication of this activity. CME Editor, Anne F. Eder, MD, PhD reported no conflicts of interest or financial relationships relevant to this article. The authors reported no conflicts of interest or financial relationships relevant to this article. This activity underwent peer review in line with the standards of editorial integrity and publication ethics. Conflicts of interest have been identified and resolved in accordance with John Wiley and Sons, Inc.’s Policy on Activity Disclosure and Conflict of Interest.