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The feasibility and efficacy of subcutaneous plerixafor for mobilization of peripheral blood stem cells in allogeneic HLA–identical sibling donors: results of the HOVON‐107 study

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Plerixafor (PFX) mobilizes CD34+ cells into circulation by disrupting the CXCR4 binding of the hematopoietic stem cell in its bone marrow niche. Click to show full abstract

Plerixafor (PFX) mobilizes CD34+ cells into circulation by disrupting the CXCR4 binding of the hematopoietic stem cell in its bone marrow niche.

Keywords: mobilization peripheral; efficacy subcutaneous; subcutaneous plerixafor; stem; feasibility efficacy; plerixafor mobilization

Journal Title: Transfusion
Year Published: 2019

Link to full text (if available)


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