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Platelet storage is often complicated by deleterious changes that are started by reversible activation of the cells and can lead to procoagulant function and apoptosis during longer periods of storage.… Click to show full abstract
Platelet storage is often complicated by deleterious changes that are started by reversible activation of the cells and can lead to procoagulant function and apoptosis during longer periods of storage. Given that increasing levels of reactive oxygen species (ROS) generation are associated with platelet activation and apoptosis, our study investigated whether ROS scavenging or the inhibition of ROS production can enhance the viability of stored platelets.
Keywords:
storage;
viability;
cysteine nox;
scavenger acetyl;
ros scavenger;
acetyl cysteine
Journal Title: Transfusion
Year Published: 2019
Link to full text (if available)
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Journal Title: Transfusion
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!