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Optimal titer of anti‐HBs in blood components derived from donors with anti‐HBc

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The ultimate strategy to cope with transfusion‐transmitted hepatitis B virus (HBV) infection caused by transfusion of blood from donors with historical HBV infection is to reject all donors having anti‐HBV… Click to show full abstract

The ultimate strategy to cope with transfusion‐transmitted hepatitis B virus (HBV) infection caused by transfusion of blood from donors with historical HBV infection is to reject all donors having anti‐HBV core antigen (anti‐HBc). However, this strategy would result in a huge loss of blood donors and subsequent blood inventory collapse. On the other hand, anti‐HBc–positive blood is reportedly not infectious when containing more than 100 mIU/mL of anti‐HBV surface antigen (anti‐HBs).

Keywords: anti hbc; blood; donors anti; anti hbs

Journal Title: Transfusion
Year Published: 2019

Link to full text (if available)


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