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Granulocyte transfusions made with modified fluid gelatin in pediatric and adolescent patients with prolonged neutropenia

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Granulocyte transfusions (GT) are used to treat progressive systemic or local infections in prolonged neutropenic patients with antibiotic or antifungal resistance. Granulocytes are most commonly collected from whole blood by… Click to show full abstract

Granulocyte transfusions (GT) are used to treat progressive systemic or local infections in prolonged neutropenic patients with antibiotic or antifungal resistance. Granulocytes are most commonly collected from whole blood by apheresis using hydroxyethyl starch (HES) as the red blood cell (RBC) sedimentation agent. This is the first study on the safety and efficacy of transfusing granulocytes collected with modified fluid gelatin (MFG) instead of HES to pediatric patients.

Keywords: granulocyte transfusions; fluid gelatin; modified fluid; transfusions made

Journal Title: Transfusion
Year Published: 2021

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