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Allo‐antibodies produced by K‐negative pregnant women against a fetal K antigen from the Kell blood group system may cause hemolytic disease of the fetus and newborn (HDFN). Predicting the fetal… Click to show full abstract
Allo‐antibodies produced by K‐negative pregnant women against a fetal K antigen from the Kell blood group system may cause hemolytic disease of the fetus and newborn (HDFN). Predicting the fetal K antigen using noninvasive prenatal testing (NIPT) is important for decisions concerning management of pregnancies. Digital and droplet digital PCR techniques permit the detection of fetal single nucleotide variant with a higher specificity and sensitivity than real‐time polymerase chain reaction (PCR).
Keywords:
diagnostics fetal;
kel allele;
fetal kel;
digital pcr;
pcr;
noninvasive diagnostics
Journal Title: Transfusion
Year Published: 2022
Link to full text (if available)
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Journal Title: Transfusion
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!