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Mitigating the risk of transfusion‐transmitted infections with vector‐borne agents solely by means of pathogen reduction

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This study evaluated whether pathogen reduction technology (PRT) in plasma and platelets using amotosalen/ultraviolet A light (A/UVA) or in red blood cells using amustaline/glutathione (S‐303/GSH) may be used as the… Click to show full abstract

This study evaluated whether pathogen reduction technology (PRT) in plasma and platelets using amotosalen/ultraviolet A light (A/UVA) or in red blood cells using amustaline/glutathione (S‐303/GSH) may be used as the sole mitigation strategy preventing transfusion‐transmitted West Nile (WNV), dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV) viral, and Babesia microti, Trypanosoma cruzi, and Plasmodium parasitic infections.

Keywords: transfusion transmitted; risk transfusion; pathogen reduction; mitigating risk; transfusion

Journal Title: Transfusion
Year Published: 2022

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