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Cold‐stored platelets are effective in an in vitro model of massive transfusion protocol assessed by rotational thromboelastometry

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Platelets are a key component of massive transfusion in treating actively bleeding patients. While optimized for prophylactic transfusions, the effectiveness of the current standard room temperature stored platelets (RPs) in… Click to show full abstract

Platelets are a key component of massive transfusion in treating actively bleeding patients. While optimized for prophylactic transfusions, the effectiveness of the current standard room temperature stored platelets (RPs) in treating actively bleeding patients is not clear. Cold‐stored platelets (CPs) have been shown to have superior hemostatic functions and the potential to extend shelf life. In this study, we explored the effect of using CPs versus RPs in an in vitro transfusion model based on the massive transfusion protocol.

Keywords: massive transfusion; model; stored platelets; transfusion; transfusion protocol; cold stored

Journal Title: Transfusion
Year Published: 2022

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