LAUSR

The ABO blood group system was the first human blood group to be discovered and is of great signifi-cance in transfusion medicine. Currently, it needs to perform compatibility for ABO blood group in clinical blood transfusion. 1 The ABO gene consists of seven coding exons, which encode one of two different glyco-syltransferases to form A or B antigens respectively. 2 There are only four antigens in the ABO blood group system, but any polymorphism or variation that changes the activity or specificity of the glycosyltrans-ferases will be altered the ABO phenotype. Now, over 400 ABO alleles were found in the ABO subgroup of individuals from around the world. 3 Here, we reported a novel variation, c.977A>C, on the ABO*A1.02 allele that was associated with an A W phenotype