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Patients with severe thrombocytopenia due to bone marrow failure and after chemotherapy are still treated with platelet transfusions. Platelet concentrates (PC) are associated with a high incidence of adverse reactions… Click to show full abstract
Patients with severe thrombocytopenia due to bone marrow failure and after chemotherapy are still treated with platelet transfusions. Platelet concentrates (PC) are associated with a high incidence of adverse reactions (AR). Platelet‐derived damage‐associated molecular patterns (DAMPS) and complement were proposed to play a role in the pathology of AR.
Keywords:
adverse reactions;
concentrates induce;
complement activation;
damps complement;
platelet concentrates;
activation platelet
Journal Title: Transfusion
Year Published: 2022
Link to full text (if available)
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Journal Title: Transfusion
Year Published: 2022
Link to full text (if available)
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recommendations!