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Hemolytic disease of the fetus and newborn caused by anti‐sD antibody in a GP.Mur/Mur Thai mother and review of the prevalence of sD in Thai blood donors

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Low‐prevalence antigen sD (MNS23) is encoded by GYPB c.173C > G. Hemolytic disease of the fetus and newborn (HDFN) due to anti‐sD is rare. A mother delivered a newborn whose red blood… Click to show full abstract

Low‐prevalence antigen sD (MNS23) is encoded by GYPB c.173C > G. Hemolytic disease of the fetus and newborn (HDFN) due to anti‐sD is rare. A mother delivered a newborn whose red blood cells (RBCs) were DAT‐positive and was later diagnosed with HDFN. Serum from the mother was incompatible with the father's RBCs and was used to screen 184 Thai blood donors. This study aimed to investigate the cause of HDFN in a Thai family and determine the prevalence of sD in Thai blood donors.

Keywords: thai; blood donors; prevalence; mur; blood; thai blood

Journal Title: Transfusion
Year Published: 2022

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