Four amino acids are involved in epitope formation of human neutrophil antigens (HNA)‐1 alleles, located at positions 36, 65, 78, and 82. HNA‐1a and HNA‐1b alloantibody epitopes were recently characterized.… Click to show full abstract
Four amino acids are involved in epitope formation of human neutrophil antigens (HNA)‐1 alleles, located at positions 36, 65, 78, and 82. HNA‐1a and HNA‐1b alloantibody epitopes were recently characterized. The HNA‐1b allele also carries the HNA‐1d epitope p.78A&p.82N. The current study aimed to identify compound antibody specificities in HNA‐1b alloantisera, especially the presence of anti‐HNA‐1d.
               
Click one of the above tabs to view related content.