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Bacterial culture time to detection in platelet components: An evidence synthesis and estimation of detection failures

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Non‐pathogen reduction platelet bacterial risk control strategies in the US FDA guidance include at least one culture. Almost all of these strategies have a culture hold time of ≥12 h. Studies… Click to show full abstract

Non‐pathogen reduction platelet bacterial risk control strategies in the US FDA guidance include at least one culture. Almost all of these strategies have a culture hold time of ≥12 h. Studies have reported time to detection (TTD) of bacterial cultures inoculated with bacteria from contaminated platelets, but these data and estimates of risk associated with detection failures have not been synthesized.

Keywords: culture; detection failures; detection; platelet; time detection

Journal Title: Transfusion
Year Published: 2022

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