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The administration of anti‐D for the prevention of hemolytic disease of the fetus and newborn is one of the most successful clinical uses of the phenomenon of antibody‐mediated immune suppression… Click to show full abstract
The administration of anti‐D for the prevention of hemolytic disease of the fetus and newborn is one of the most successful clinical uses of the phenomenon of antibody‐mediated immune suppression (AMIS). However, despite adequate prophylaxis, failures can still occur in the clinic and are poorly understood. Recently, the copy number of red blood cell (RBC) antigens has been shown to influence immunogenicity in the context of RBC alloimmunization; however, its influence on AMIS remains unexplored.
Keywords:
immune suppression;
antibody mediated;
mediated immune;
copy number;
antibody
Journal Title: Transfusion
Year Published: 2023
Link to full text (if available)
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Journal Title: Transfusion
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!