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Evaluation of pancreatic duct cannulation methods for human islet isolation

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In this letter, we provide data for the first time on the comparison of two cannulation methods used in human islet isolation: single cannula method (SCM) vs. dual cannula method… Click to show full abstract

In this letter, we provide data for the first time on the comparison of two cannulation methods used in human islet isolation: single cannula method (SCM) vs. dual cannula method (DCM). Islet Transplantation is an effective treatment for patients with refractory chronic pancreatitis (CP) and Type 1 Diabetes (T1D). Sufficient islets is required for achieving manageable metabolic status after transplantation. Collagenase infusion through the pancreatic duct is critical, as improper distention leads to poor yield (1). This article is protected by copyright. All rights reserved.

Keywords: pancreatic duct; islet isolation; cannulation methods; islet; human islet

Journal Title: Transplant International
Year Published: 2019

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