Successful renal transplantation requires lifelong immunosuppression, usually with a combination of drugs, to prevent rejection and immunologically-mediated damage to the graft. To achieve maximum effect, these immunosuppressive agents must be… Click to show full abstract
Successful renal transplantation requires lifelong immunosuppression, usually with a combination of drugs, to prevent rejection and immunologically-mediated damage to the graft. To achieve maximum effect, these immunosuppressive agents must be taken regularly as prescribed. This is particularly true of critical-dose drugs such as tacrolimus, with a narrow therapeutic window between efficacy and toxicity. This article is protected by copyright. All rights reserved.
               
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