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New aspects on the efficacy of high‐dose intravenous immunoglobulins in patients with autoimmune thrombocytopenia

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The clinical significance of autoimmune thrombocytopenia (ITP) is reflected by bleeding and/or an increased bleeding risk due to low platelet counts. In most cases, treatment with high‐dose (1–2 g/kg body… Click to show full abstract

The clinical significance of autoimmune thrombocytopenia (ITP) is reflected by bleeding and/or an increased bleeding risk due to low platelet counts. In most cases, treatment with high‐dose (1–2 g/kg body weight) intravenous immunoglobulin has been demonstrated to result in an increase in platelet counts after one day of treatment. Until now, there is little information on the true beginning of therapy effect in patients treated with high‐dose intravenous immunoglobulin. In this study, we focused on the kinetic of platelet counts and cessation of bleeding within the first 24 h of treatment.

Keywords: high dose; dose intravenous; new aspects; platelet counts; autoimmune thrombocytopenia; aspects efficacy

Journal Title: Vox Sanguinis
Year Published: 2017

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