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Change of the metabolomic profile during short‐term mononuclear cell storage

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Short‐term storage of leukapheresis products used for immunotherapeutic mononuclear cell (MNC) products is a frequent event. The analysis of time‐related metabolic patterns enables the characterization of storage‐related effects in MNCs… Click to show full abstract

Short‐term storage of leukapheresis products used for immunotherapeutic mononuclear cell (MNC) products is a frequent event. The analysis of time‐related metabolic patterns enables the characterization of storage‐related effects in MNCs and the hypothesis‐based optimization of the MNC medium.

Keywords: storage; short term; change metabolomic; mononuclear cell

Journal Title: Vox Sanguinis
Year Published: 2017

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