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Novel intronic RHD variants identified in serologically D‐negative blood donors

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Blood group genotyping is used to predict RhD phenotype in transfusion and obstetric medicine. Prediction of antigen D is based on molecular techniques which targets most common RHD‐specific polymorphism. However,… Click to show full abstract

Blood group genotyping is used to predict RhD phenotype in transfusion and obstetric medicine. Prediction of antigen D is based on molecular techniques which targets most common RHD‐specific polymorphism. However, inactive RHD variants can suggest false‐positive RhD phenotype. Their types and frequencies vary among ethnicities. Our study aimed to identify RHD variants among Moroccan blood donors who are serologically D negative.

Keywords: blood donors; novel intronic; rhd variants; serologically negative; rhd

Journal Title: Vox Sanguinis
Year Published: 2017

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