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Risk of RBC alloimmunization in multiple myeloma patients treated by Daratumumab

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Daratumumab (DARA) is a human monoclonal antibody for the treatment of multiple myeloma (MM). DARA binds to CD38 on RBCs and interferes with detection of RBC alloantibodies. The objective of… Click to show full abstract

Daratumumab (DARA) is a human monoclonal antibody for the treatment of multiple myeloma (MM). DARA binds to CD38 on RBCs and interferes with detection of RBC alloantibodies. The objective of this study was to evaluate the risk of RBC alloimmunization in MM patients treated with DARA.

Keywords: multiple myeloma; rbc alloimmunization; risk rbc; patients treated

Journal Title: Vox Sanguinis
Year Published: 2019

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