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Pro‐inflammatory effects after platelet transfusion: a review

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Platelet has been linked to thrombosis in several studies. Inflammation is closely intertwined with thrombosis and occurs consecutively; it is therefore conceivable that platelet transfusions perform an increasingly vital role… Click to show full abstract

Platelet has been linked to thrombosis in several studies. Inflammation is closely intertwined with thrombosis and occurs consecutively; it is therefore conceivable that platelet transfusions perform an increasingly vital role in inflammation. As platelet transfusions have been a significant therapeutic approach in patients for decades, serious risks including viral transmission, bacterial sepsis and acute lung injury have been demonstrated by retrospective studies and randomized clinical trials. Recent data suggest associations among platelet transfusion and pro‐inflammatory responses.

Keywords: platelet transfusion; transfusion review; inflammatory effects; effects platelet; pro inflammatory

Journal Title: Vox Sanguinis
Year Published: 2020

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