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Deferasirox‐associated Fanconi syndrome in adult patients with transfusional iron overload

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Deferasirox is an oral chelator approved for iron overload, which has a potential side effect of renal Fanconi syndrome, with proximal tubular dysfunction and tubular acidosis. Monitoring of renal function… Click to show full abstract

Deferasirox is an oral chelator approved for iron overload, which has a potential side effect of renal Fanconi syndrome, with proximal tubular dysfunction and tubular acidosis. Monitoring of renal function is recommended, though no standard for monitoring exists. We aim to describe cases of deferasirox‐associated Fanconi syndrome in adults and the renal monitoring required to detect these findings.

Keywords: deferasirox associated; iron overload; associated fanconi; fanconi syndrome

Journal Title: Vox Sanguinis
Year Published: 2021

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