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In vitro storage characteristics of neonatal platelet concentrates after addition of 20% PAS‐E

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An observed decline in end‐of‐storage pH in plateletpheresis‐derived platelet concentrates for neonatal use suspended in 100% autologous plasma was expected to be reversed by the addition of a platelet additive… Click to show full abstract

An observed decline in end‐of‐storage pH in plateletpheresis‐derived platelet concentrates for neonatal use suspended in 100% autologous plasma was expected to be reversed by the addition of a platelet additive solution, (PAS)‐E, increasing unit volume by approximately 20%. This study determined the impact on other in vitro storage parameters to ensure the expected increase in pH did not mask an adverse impact on component quality.

Keywords: vitro storage; storage characteristics; addition; platelet concentrates; platelet; storage

Journal Title: Vox Sanguinis
Year Published: 2022

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