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Differential enzymatic deglycosylation reveals attachment of red cell B antigen onto the carbohydrate moiety of glycophorin A and glycophorin B

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Early studies indicate that red cell A and B antigens are attached primarily onto band 3 and GLUT1 on the erythrocyte membrane and little onto glycophorin A (GPA) and glycophorin… Click to show full abstract

Early studies indicate that red cell A and B antigens are attached primarily onto band 3 and GLUT1 on the erythrocyte membrane and little onto glycophorin A (GPA) and glycophorin B (GPB). But as GPA and band 3 form stable protein complexes and GPA is much more heavily glycosylated than band 3, this study re‐examined the association between ABO antigens and GPA/GPB.

Keywords: red cell; differential enzymatic; glycophorin; deglycosylation reveals; enzymatic deglycosylation

Journal Title: Vox Sanguinis
Year Published: 2022

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