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Pathogen reduction with methylene blue does not have an impact on the clinical effectiveness of COVID‐19 convalescent plasma

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There is a concern about a possible deleterious effect of pathogen reduction (PR) with methylene blue (MB) on the function of immunoglobulins of COVID‐19 convalescent plasma (CCP). We have evaluated… Click to show full abstract

There is a concern about a possible deleterious effect of pathogen reduction (PR) with methylene blue (MB) on the function of immunoglobulins of COVID‐19 convalescent plasma (CCP). We have evaluated whether MB‐treated CCP is associated with a poorer clinical response compared to other inactivation systems at the ConPlas‐19 clinical trial.

Keywords: methylene blue; pathogen reduction; reduction methylene; covid convalescent; convalescent plasma

Journal Title: Vox Sanguinis
Year Published: 2023

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