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A systematic review of criteria used to report complications in soft tissue and oncologic surgical clinical research studies in dogs and cats

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Abstract Objective To evaluate reporting of surgical complications and other adverse events in clinical research articles describing soft tissue and oncologic surgery in dogs and cats. Study design Systematic literature… Click to show full abstract

Abstract Objective To evaluate reporting of surgical complications and other adverse events in clinical research articles describing soft tissue and oncologic surgery in dogs and cats. Study design Systematic literature review. Sample English‐language articles describing soft tissue and oncologic surgeries in client‐owned dogs and cats published in peer‐reviewed journals from 2013 to 2016. Methods CAB, AGRICOLA, and MEDLINE databases were searched for eligible articles. Article characteristics relevant to complications were abstracted and summarized, including reported events, definitions, criteria used to classify events according to severity and time frame, and relevant citations. Results One hundred fifty‐one articles involving 10 522 animals were included. Canine retrospective case series of dogs predominated. Ninety‐two percent of articles mentioned complications in study results, but only 7.3% defined the term complication. Articles commonly described complications according to time frame and severity, but terminology and classification criteria were highly variable, conflicting between studies, or not provided. Most (58%) reported complications could have been graded with a published veterinary adverse event classification scheme, although common intraoperative complications were notable exceptions. Conclusion Definitions and criteria used to classify and report soft tissue and oncologic surgical complications are often absent, incomplete, or contradictory among studies. Clinical significance Lack of consistent terminology contributes to inadequate communication of important information about surgical complications. Standardization of terminology and consistency in severity scoring will improve comparative evaluation of clinical research results.

Keywords: criteria used; soft tissue; tissue oncologic; dogs cats; clinical research

Journal Title: Veterinary Surgery
Year Published: 2019

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