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Neonatal pigs have the potential to provide an inexhaustible source of islets for the treatment of type 1 diabetes. However, the immunological barriers to islet xenotransplantation still need to be… Click to show full abstract
Neonatal pigs have the potential to provide an inexhaustible source of islets for the treatment of type 1 diabetes. However, the immunological barriers to islet xenotransplantation still need to be overcome. A better understanding of the xeno‐specific immune responses that are involved in neonatal porcine islet (NPI) xenotransplant rejection will help to facilitate the identification of new targets for anti‐rejection therapies, and thus enable more specific targeting of the immune cells and molecules involved.
Keywords:
neonatal porcine;
early immune;
rejection;
porcine islet;
immune mechanisms
Journal Title: Xenotransplantation
Year Published: 2019
Link to full text (if available)
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Journal Title: Xenotransplantation
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!