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Characterization of chelator‐mediated recovery of pancreatic islets from barium‐stabilized alginate microcapsules

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Islet recovery from within alginate‐based microcapsules is necessary for certain analytical assays like flow cytometry; however, this technology has not been widely characterized. In this study, we explore the ability… Click to show full abstract

Islet recovery from within alginate‐based microcapsules is necessary for certain analytical assays like flow cytometry; however, this technology has not been widely characterized. In this study, we explore the ability of EDTA, EGTA, and sodium citrate to induce reverse alginate polymerization via chelation and assess the toxicity of each chelator on pancreatic islets.

Keywords: recovery; chelator mediated; characterization chelator; mediated recovery; pancreatic islets

Journal Title: Xenotransplantation
Year Published: 2019

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